Staff Software Engineer, Variant Classification
Core
Design and build tools to define, store, and provide variant/sample/test level information for accurate variant interpretation and report generation in genetic diagnostics.
Role type
Staff Software Engineer (Genomic Data Platform)
Builds
Variant classification tools, bioinformatic data processing systems, and evidence placement automation for genetic testing platforms.
Domain
Healthcare / Genomics / Bioinformatics
Required skills
Python, relational databases, web development frameworks, front-end technologies (React/Angular/Vue), RESTful APIs, microservices, CI/CD pipelines, cloud platforms (AWS/Azure/GCP)
Preferred skills
Bioinformatics/Computational Biology domain knowledge, mentoring senior engineers, technical vision & roadmap definition, bioinformatic tools & annotation, variant databases (ClinVar/gnomAD/HGMD), Spark/NLP/ML, biomedical terminologies (MeSH/NCIt/HGNC)
Technologies
Python, React, Angular, Vue.js, JavaScript/TypeScript, AWS, Azure, GCP, Spark, GitHub Copilot, Claude Code
Responsibilities
Design and build tools for variant/sample/test information storage; develop systems translating raw bioinformatic data into variant information; scale and optimize storage for growing data needs; source and maintain variant-level annotations; automate evidence placement and classification; support test content and assay development initiatives.
Seniority
Staff, hands-on IC with strategic influence
