Principal Scientist - Protein Mass Spectrometry

UK - Hertfordshire - Stevenage💼 Full-time🗓 2026-09-29

Core

Lead protein mass spectrometry analysis to generate analytical understanding for early-phase biopharmaceutical projects, supporting decisions on biotherapeutics, process development, and product quality.

Role type

Principal Scientist (Protein Mass Spectrometry)

Builds

Analytical strategies and data for biotherapeutic characterization

Domain

Biopharmaceuticals / Analytical Chemistry

Required skills

Mass spectrometry (Orbitrap, Q-TOF), LC-MS/LC-MS/MS, protein biochemistry, experimental planning, data analysis, technical communication

Preferred skills

Protein glycosylation analysis, advanced MS workflows (host-cell protein, sequence variants), automated data pipelines, data visualization/programming (Python, R, SQL), liquid-handling automation

Technologies

Orbitrap, Q-TOF, LC-MS, Spotfire, Power BI, JMP, SIMCA, SQL, Python, R

Responsibilities

Perform analytical characterization of biotherapeutics; develop and optimize analytical methods; support technology transfer and forced-degradation studies; plan and deliver complex experiments; collaborate across Discovery and CMC teams; maintain data integrity and lab safety

Seniority

Principal, hands-on IC with strategic input

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About gsk

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.