Scientist R&D – Immunohistochemistry (IHC) & Histology
Core
Develop, optimize, verify, and validate Immunohistochemistry (IHC) and histology workflows for oncology product development and clinical assay support.
Role type
Scientist R&D (Immunohistochemistry & Histology)
Builds
Oncology diagnostic products and clinical laboratory workflows
Domain
Oncology / Molecular Diagnostics / Histopathology
Required skills
IHC assay development and optimization, Histology and FFPE tissue workflows, Automated IHC/ISH platform operation, Antibody characterization and titration, Antigen retrieval, Tissue morphology analysis, Assay validation in regulated environments
Preferred skills
Roche BenchMark ULTRA IHC/ISH System experience, NGS and molecular biology workflows, Digital pathology and image analysis, PCR/qPCR, LDT environment experience
Technologies
Roche BenchMark ULTRA, Excel, JMP
Responsibilities
Design and execute development and validation studies for IHC and histology workflows, Develop and optimize IHC assays including antibody selection and staining conditions, Evaluate and optimize histology variables including fixation and sectioning, Troubleshoot automated staining platforms and investigate staining artifacts, Plan and execute moderate- to high-complexity experiments and analyze results, Collaborate with cross-functional teams to transfer R&D methods into clinical workflows, Author study protocols, validation reports, and SOPs
Seniority
Mid-level, hands-on IC