Research Scientist II - In Vivo Science
Core
Design, execute, and analyze in vivo studies to evaluate drug candidates in physiologically relevant settings and inform go/no-go decisions for pipeline programs.
Role type
Senior IC research scientist (in vivo pharmacology)
Builds
Preclinical efficacy data and validated animal models for antibody-based medicine programs
Domain
Biotechnology / Oncology / Immunology
Required skills
in vivo pharmacology model design, PK/PD assessment, efficacy study execution, animal research ethics, biomarker modulation analysis, ex vivo experimental planning, scientific reporting, project management, cross-functional collaboration, mentorship
Preferred skills
oncology drug development experience, immuno-oncology expertise, biologics development knowledge, CRO management, novel model development
Technologies
none stated
Responsibilities
Define preclinical in vivo strategy for pipeline programs; design and validate novel animal models; execute and interpret in vivo efficacy and pharmacology studies; collaborate with in vitro, protein engineering, and PK/PD teams; develop and supervise sample analysis for target engagement and pathway effects; train and mentor junior scientists; synthesize and report complex research findings to leadership
Seniority
Mid-Senior, hands-on IC