Scientist, LNP Process and Development
Core
Develop and scale-up lipid nanoparticle (LNP) formulations for nucleic acid delivery, focusing on process optimization and manufacturing of targeted LNPs encapsulating modified DNA and cofactor mRNA.
Role type
Scientist, LNP Process and Development
Builds
Scalable and robust nucleic acid delivery systems (LNPs)
Domain
Biotechnology / Gene Therapy / Nucleic Acid Delivery
Required skills
Process development, Scale-up, Nanoparticle formulation, Experimental design, Data analysis, Technical problem solving
Preferred skills
Nucleic acid formulation (mRNA/DNA), T-mixing, DLS, Encapsulation assays
Technologies
T-mixing, DLS
Responsibilities
Optimize LNP formulation mixing parameters and encapsulation efficiency; Design and execute experiments to improve LNP performance and manufacturability; Collaborate on characterization and evaluation of LNP formulations; Assist with technology transfer and scale-up coordination; Analyze experimental data and maintain documentation.
Seniority
Mid-level Scientist (3+ years experience)