Director, Clinical Research

United States💼 Full-time💰 $255,000–$255,000🗓 2026-06-30 → 2026-09-05

Core

Lead clinical development for RNAi therapeutics in ATTR amyloidosis, driving strategies from bench-to-bedside and securing global regulatory approvals.

Role type

Director, Clinical Research (Physician-Scientist)

Builds

Clinical trials and regulatory submissions for RNAi therapeutics

Domain

Biopharmaceuticals / RNAi therapeutics / Cardiology

Required skills

Clinical trial design, regulatory strategy, medical judgment, leadership in matrix environments, scientific writing, stakeholder influence

Preferred skills

Heart failure expertise, amyloidosis expertise, biotech/pharma partner experience

Technologies

Clinical trial management systems, regulatory submission platforms

Responsibilities

Provide strategic leadership for clinical programs, oversee trial conduct and safety, consult on novel target feasibility, supervise regulatory documents and protocols, influence internal and external audiences

Seniority

Director, strategic leadership with hands-on clinical oversight

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About alnylam

We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakth