Sr Scientist, Inflammation Biomarkers and Translational Research
Core
Lead end-to-end biomarker strategy for clinical programs from translational research through Phase I-III and registrational studies, defining pharmacodynamic and disease-monitoring biomarkers.
Role type
Senior Scientist, Translational Medicine & Biomarker Strategy
Builds
Clinical biomarker strategies, validated assays, and regulatory documentation for inflammatory and fibrotic disease therapies
Domain
Biopharmaceuticals, Immunology, Inflammation Biology, Translational Medicine
Required skills
Human immunology, assay qualification and validation, clinical trial design (Phase I-III), regulatory document authoring, cross-functional leadership, data integration (multi-omic, imaging), scientific publication
Preferred skills
Liver/gut biology and fibrotic mechanisms, health authority interaction (FDA/EMA), high-dimensional platforms (flow/mass cytometry, single-cell, spatial), data analysis (R, Python)
Technologies
R, Python, flow cytometry, mass cytometry, single-cell sequencing, spatial imaging, digital pathology
Responsibilities
Lead biomarker strategy for clinical programs; define and validate pharmacodynamic and prognostic biomarkers; oversee human-relevant translational studies; integrate multi-omic and clinical datasets; author regulatory documents; present data at conferences and meetings; mentor junior scientists
Seniority
Senior, hands-on IC with strategic leadership
