Scientist, Oncology Research
Core
Investigate molecular mechanisms driving cancer cell identity, tumor maintenance, and therapeutic response via protein and nucleic acid biochemistry.
Role type
Early discovery oncology scientist (protein-nucleic acid biochemistry)
Builds
Novel therapeutic hypotheses and discovery-stage programs
Domain
Oncology / Molecular Biology / Biochemistry
Required skills
protein-nucleic acid biochemistry, biophysical approaches, mammalian cell culture, molecular biology techniques, target identification, mechanism-of-action studies
Preferred skills
reconstitution of endogenous multi-subunit protein complexes, ribonucleoprotein complex characterization, SPR/BLI/fluorescence polarization/ITC/EMSA, transcriptional regulation, RNA biology, chromatin regulation
Technologies
SPR, BLI, fluorescence polarization, ITC, EMSA
Responsibilities
Design and execute experiments on protein-nucleic acid complexes; characterize protein-protein and protein-nucleic acid interactions; generate mechanistic insights into oncogenic pathways; collaborate across multidisciplinary teams; communicate scientific findings
Seniority
Mid-Senior, hands-on IC