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Principal Scientist, Translational Informatics and Predictive Sciences

Cambridge Crossing - MA - US💼 Full-time💰 $166,770–$166,770🗓 2026-09-30 → 2026-10-01

Core

Apply bioinformatics, statistical, and computational biology approaches to analyze large-scale clinical and real-world datasets to discover biomarkers and inform development strategies for solid tumor oncology medicines.

Role type

Principal Scientist, Translational Informatics and Predictive Sciences

Builds

Data-driven insights for next-generation oncology medicines

Domain

Biopharma, Oncology, Computational Biology, Machine Learning

Deliverable

production ML models

Required skills

High-throughput molecular data analysis, R, Python, AI/ML methods, Statistical modeling, Multi-omics integration, Biomarker discovery

Preferred skills

Spatial omics, Oncology domain expertise, Drug development experience

Technologies

Next-generation sequencing, Single-cell technologies, Proteomics, Agentic AI coding tools

Responsibilities

Partner with clinical and preclinical teams to design computational strategies for translational studies; Analyze high-dimensional molecular datasets to generate mechanistic insights; Apply and develop ML/AI methods for predictive modeling and data integration; Provide scientific leadership and mentorship on analytical best practices; Communicate scientific results to decision-making bodies to influence cross-functional strategy

Seniority

Principal, hands-on IC with strategic impact

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