Clinical Lead Early Clinical and Experimental Therapeutics
Core
Lead early clinical development (Phase 1a/b, 2a) and experimental therapeutics studies to validate human targets and support Go/No-Go decisions for novel modalities including small molecules, antibodies, peptides, and gene therapies.
Role type
Senior Clinical Lead / Study Medical Manager (SMM)
Builds
First-in-human studies, natural history studies, mechanistic trials, and early clinical development plans
Domain
Biopharmaceutical R&D, Translational Medicine, Early Clinical Development
Required skills
early clinical trial design, dose selection, safety monitoring, protocol development, regulatory document authoring, cross-functional team leadership, data interpretation, Go/No-Go decision making
Preferred skills
translational research mindset, broad biomedical knowledge, laboratory research experience, late-phase clinical trial experience
Technologies
none stated
Responsibilities
Design early development plans and First-In-Human studies; supervise study execution and medical monitoring; review and interpret clinical data; author clinical protocols, reports, and regulatory documents; lead dose escalation meetings; ensure compliance with clinical trial standards; present data to internal and external stakeholders
Seniority
Senior, hands-on IC with study management authority